I like to lay out my boundaries with electrical tape, as you can manipulate the tape and make curved lines with it, rather than using masking tape, and having to use multiple pieces to make your curves. Then, once I see how I like it, I like to cut near the boundary, but not up to it, using a hacksaw blade by hand, while wearing a pair of gloves (for obvious reasons). Then, once I have my rough cuts made, I like to use an aggressive grit of sandpaper (something like 24 or 36 grit) and sand almost all the way to the boundary. Then, when I'm satisfied with the shape, I use a razor blade to basically shave off the rough edges left by the sandpaper. To do this, I hold the razor blade perpendicular to the plastic. This will basically shave off the rough stuff and you'll be able to shape the edge of the fender and round it off so it resembles a factory edge, and with enough patience and a little practice, you'll get edges that are cleaner than factory. Some people like to use a razor or box cutter to just make one cut, but in my experience, it's too easy to get off track-- to slip off of your line. Then you're stuck with a gouge in your plastic. Some people try to get around this by heating the blade, but this can also be dangerous. Good luck with your endeavor.